Selected publications

1. Kovtonyuk LV, Takizawa H^*. Mouse genetic background and human hematopoietic stem cells biology; tips for humanization. Humanized Mice for HIV Research, Springer, 2015, ^*correspondance
2. Nakamura-Ishizu A, Takizawa H, Suda T, The analysis, roles and regulation of quiescence in hematopoietic stem cells. Development 15: 4656-66, 2014
3. Lundberg P^#, Takizawa H^#, Kubovcakova L^#, Guo G, Hao-Shen H, Dirnhofer S, Orkin SH, Manz MG, Skoda RC. Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F J Exp Med., 2014 Oct 20;211(11):2213-30., ^#equal contribution
4. Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J , Ruzo A, Lupo PJ, Hicks  MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Heym KM, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE.BRAF-V600E Expression in Precursor Versus Differentiated Dendritic Cells Defines Clinically Distinct LCH Risk-Groups. J Exp Med., 2014 Apr 7;211(4):669-83. doi: 10.1084/jem.20130977. Epub 2014 Mar 17.
5. Rongvaux A, Takizawa H, Strowig T, Willinger T, Eynon EE, Flavell RA, Manz MG. Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine. Annu Rev Immunol., 2013 Jan 16, 2013 Mar 5;110(10):3997-4002.
6. Scotti C^#, Piccinini E^#, Takizawa H^#, Todorov A, Bourgine P, Papadimitropoulos A, Barbero A, Manz MG, Martin I. Engineering of a functional bone organ through endochondral ossification. Proc Natl Acad Sci U S A., 2013, Mar 5;110(10):3997-4002, ^#equal contribution
7. Takizawa H^*, Manz MG. In vivo divisional tracking of hematopoietic stem cells. Ann N Y Acad Sci., 2012 Aug;1266(1):40-6. doi: 10.1111/j.1749-6632.2012.06500.x. ^*correspondance
8. Takizawa H, Boettcher S, Manz MG. Demand-adapted regulation of early hematopoiesis in infection and inflammation. Blood., 2012 Mar 29;119(13):2991-3002.
9. Takizawa H^#, Regoes RR^#, Boddupalli CS, Bonhoeffer S, Manz MG. Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation. J Exp Med., 2011 Feb; 14;208(2):273-84., ^#equal contribution
10. Takizawa H^#, Nishimura S^#, Nishikii H, Takayama N, Oda A, Kakinuma S, Morita Y, Yamazaki S, Tamura N, Goto S, Sawaguchi A, Manabe I, Takatsu Ki, Nakauchi H, Takaki S, Eto K. Lnk/Sh2b3 regulates integrin αIIbβ3 outside in signaling in platelets leading to stabilization of developing thrombus in vivo. J Clin Invest., 2010 Jan;120(1):179-90., ^#equal contribution
11. Takizawa H, Eto K, Yoshikawa A, Nakauchi H, Takatsu K, Takaki S, Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals. Exp Hematol., 2008 Jul; 36(7): 897-906
12. Takizawa H, Manz MG, Macrophage tolerance: CD47-SIRP-alpha-mediated signals matter. Nat Immunol., 2007 Dec; 8(12): 1287-9.
13. Takizawa H, Kubo-Akashi C, Nobuhisa I, Kwon SM, Iseki M, Taga T, Takatsu K, Takaki S. Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk. Blood., 2006 Apr 1; 107(7): 2968-75.
    
    For complete list of publications, please refere to the link.
    
    

Awards